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Alprazolam for Anxiety- Benefits and Risks

Anxiety Disorder
Alprazolam for Anxiety- Benefits and Risks

Alprazolam for anxiety

Battling anxiety, worry, or fear is far more common than you think. Anxiety can be defined as distress or uneasiness of your mind caused by fear of danger or misfortune. It is worry without deceptive cause. Anxiety is one of the most common mental disorders that most people can suffer from or have endured before. Having anxiety is so discouraging and exhausting and isn’t something fun to have, either.

However, there are several ways to deal with anxiety and finally beat it down to the point where it becomes nothing. Overcoming anxiety can lead young people and elders to get over challenging experiences and difficult conditions and lead a content and peaceful life. You can overcome your anxiety using Alprazolam medication, an effective anti-anxiety medicine. In 1981, Alprazolam was approved by the USA Food and Drug Administration (FDA) for use in people suffering from anxiety or panic disorders.

This blog explores all the benefits and risks of Alprazolam medication, including its mechanism of action.

What is Alprazolam?

Alprazolam, known by various brand names, including Xanax, is the most commonly prescribed psychotropic medication in the USA. It was patented in the 1970s and manufactured by J.B. Hester at Upjohn Company (later a part of Pfizer, Inc.). Alprazolam is frequently prescribed to manage anxiety and panic disorders. It can be administered without regard to food.

Alprazolam is rapidly absorbed in your body after oral administration with a peak plasma concentration of one to two hours. Alprazolam and its metabolites are filtered out by your kidneys and excreted in your urine. The mean plasma half-life of Alprazolam is around 11.2 hours in healthy adults. You can buy Alprazolam online from walgreenusa.com if you have anxiety or panic issues, as Alprazolam is an effective anti-anxiety medicine.

Alprazolam is available as an immediate-release and orally disintegrating tablet with strengths of 0.25 milligrams, 0.5 mg, 1 mg, and 2 milligrams tablets. Alprazolam extended-release (XR) tablets are available in strengths of 0.5 milligrams, 1 mg, 2 mg, and 3 milligrams. The extended-release Alprazolam tablets are not to be crushed, chewed, or split but swallowed whole. An Alprazolam pill identifier will help you identify the different strength pills of Alprazolam. Alprazolam medicine is also available as an oral solution in the strengths of 1 mg/ 10 mL and 0.5 mg/ 5 ml. Alprazolam medication has also been subject to misuse for recreational purposes due to its disinhibition, euphoria, and anxiolytic effects.

What are the benefits of Alprazolam?

In the USA, Alprazolam is FDA-approved for treating anxiety and panic disorders. Alprazolam is an effective treatment for anxiety, panic disorder, and agoraphobia with panic attacks and works by directly blocking panic attacks. Some off-label uses of Alprazolam include insomnia, alcohol withdrawal, premenstrual syndrome, and anxiety-related depression. In some cases, it is also used for seizures. Alprazolam is as effective as conventional antidepressants in treating major depressive disorder.

Alprazolam is also sometimes used as a frontline treatment for depression. It calms electrical activity in the brain, which can help patients with anxiety and depression feel a sense of euphoria and contentment. As far back as the 1990s, Alprazolam has been shown in clinical studies to help treat major depression when prescribed in double the Alprazolam dosage used for anxiety relief for a short period.

How long does Alprazolam take to relieve anxiety?

When starting Alprazolam medication, anxiety or insomnia can improve rapidly over days or within a few hours of the first dose. Most people notice that Alprazolam will begin to work within one to two hours. Therefore, you can say that Alprazolam is a triazolobenzodiazepine that shows an immediate onset of action. It is a fast-acting drug that works quickly to treat anxiety and panic.

What is the mechanism of action of Alprazolam in treating anxiety?

Alprazolam belongs to the class of psychoactive medications known as benzodiazepines. Benzodiazepines bind to the GABA-A receptor, which consists of five subunits: alpha, beta, delta, gamma, epsilon, rho, etc. A common GABA-A receptor found in the central nervous system consists of two alpha-1—1 subunits, one gamma-2—2 subunit, and two beta—2 subunits.

The benzodiazepine binding site of Alprazolam is between the alpha- 1 and gamma- 2 subunits. Studies suggest that the alpha-1 subunit mediates the amnesia, sedation, and ataxic effects of benzodiazepines. The alpha-2 and alpha-3 subunits mediate the muscle-relaxing and anxiolytic effects. Also, research says that BNZ- 1 receptors affect anti-anxiety and sedation, while BNZ- 2 affects muscle relaxation, memory, anticonvulsant activity, and motor coordination. Benzodiazepine binding sites appear to exhibit coupling with GABA- A receptors, which enhances the effects of gamma-aminobutyric acid (or GABA) by increasing GABA affinity at the GABA- A receptor.

When bound to the GABA-A receptor, the significant inhibitory neurotransmitter GABA mediates the inhibitory or calming effects of Alprazolam on the human nervous system.

What are some good alternatives to Alprazolam for anxiety?

Clonazepam (Klonopin), diazepam (Valium), clorazepate (Tranxene), lorazepam (Ativan), estazolam (Prosom), flurazepam (Dalmane), and midazolam (Versed) are benzodiazepines which are good alternatives to Alprazolam for anxiety. However, be cautious of benzodiazepines addiction with these benzodiazepine medicines.

Is Alprazolam the same as Xanax?

Alprazolam is the generic name for Xanax. Alprazolam and its brand name version, Xanax, are benzodiazepine drugs commonly prescribed to treat anxiety and panic disorders.

Where can you buy Alprazolam online in the USA?

You can buy Alprazolam 0.25 mg online from Walgreenusa.com, the best online pharmacy store in the USA. We guarantee overnight delivery of your medicine to your doorstep.

Alprazolam and alcohol

Avoid drinking alcohol while you use Alprazolam medication. Alcohol may decrease the benefits (i.e., worsen your condition) and increase the adverse effects (such as sedation) of the Alprazolam medication.

Is Alprazolam addictive?

Alprazolam is an addictive medicine. Please read this blog further to learn more about Alprazolam addiction and withdrawal.

What are Alprazolam withdrawal syndrome risks?

Alprazolam is a controlled substance with the C- IV designation. Physiological dependence on Alprazolam is accompanied by an Alprazolam withdrawal syndrome typically characterized by irritability, sleep disturbance, panic attacks, and hand tremors. It can also cause increased tension and anxiety, sweating, difficulty concentrating, weight loss, palpitations, headache, dry retching and nausea, muscular pain and stiffness, and perceptual changes. Due to the danger of withdrawal syndrome from Alprazolam, avoid abrupt discontinuation of treatment.

The Alprazolam dosage should undergo a gradual reduction in all patients when therapy is discontinued, or the daily dosage is decreased. The suggested technique is that the daily Alprazolam dosage reduction is not by more than 0.5 milligrams every three days, and some patients might require an even slower dosage reduction. In patients with long-term chronic alprazolam usage, one should switch to a longer-acting benzodiazepine such as diazepam and clonazepam and titrate down gradually, resulting in fewer withdrawal side effects.

Risks of Alprazolam medication

Other than withdrawal, common adverse Alprazolam side effects are:

  • Drowsiness, dizziness, or tiredness
  • Sleep problems (or insomnia) and memory problems
  • Ataxia, cognitive dysfunction, poor balance, and coordination
  • Slurred speech, blurred vision, trouble concentrating, and irritability
  • Diarrhea and constipation
  • Increased sweating, nausea, vomiting, and upset stomach
  • Appetite or weight changes
  • Swelling of hands or feet, stuffy nose, dry mouth, loss of interest in sex, and muscle weakness

Alprazolam must be avoided, if possible, by anyone having a pulmonary disease. Using Alprazolam with central nervous system depressants, especially opioids, increases the risk of Alprazolam side effects such as respiratory depression, low blood pressure, and death, even more in such patients.

What are possible Alprazolam interactions?

Alprazolam is affected by medications that induce or inhibit CYP3A4. Drugs that inhibit CYP3A can increase plasma concentrations of Alprazolam. This can lead to more adverse events. Medicines known to impact Alprazolam include azole antifungals (such as ketoconazole), cimetidine, certain antidepressants (such as fluoxetine, fluvoxamine, and nefazodone), macrolide antibiotics (such as clarithromycin), rifamycins (such as rifampin), St. Johan’s wort, seizure medications (such as carbamazepine and phenytoin), antihistamines and muscle relaxants.


Alprazolam medication has several benefits, such as treating anxiety, panic, depression related to anxiety, and even insomnia in some cases. Therefore, due to this off-label use of Alprazolam, you can buy Alprazolam for sleep. However, there also are risks associated with its use.

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